The novel follows the lives of Lenny and George. It takes place in the Great Depression (1920s/1930s) in America. They support each other in a time when many are lonely and isolated.
A number comment on how unusual it is to see two people together. The men they share their lives with have a dream to hold on to and need ways of escaping from the harsh realities of the lives they live. They use prostitutes, play cards and dream of a better future.
